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What is a coinfection?

A coinfection is when there is a simultaneous infection of two viruses (a rare situation).
Ratgeber Hepatitis B-Virusinfektion (Eleni Koukoulioti, Prof. Dr. Thomas Berg) Glossar. Juni 2020


What is a secondary infection?

A secondary infection is when a patient is already a chronic carrier of a virus (like hepatitis B) and they get a second infection (for example, of hepatitis D). This is a fairly frequent occurrence.
Source: / AFEF


What is fibrosis?

It is non-specific damage characterised by hyperplasia of connective tissues with a proliferation of fibroblasts or fibrocytes that produce collagen. In short, it is a type of scarring. In the case of hepatitis, there is hepatic fibrosis which describes the scars found in the liver after years of inflammation.


What is cirrhosis?

Cirrhosis occurs when the liver uncontrollably regenerates to heal itself and forms fibrous scar tissue (fibrosis) and clusters of cells that do not follow the original architecture of the liver (nodules). Cirrhosis is the result of a prolonged hepatocyte injury. When it is complicated by active chronic hepatitis, it is called post-hepatic cirrhosis. This is a Metavir score of F4.